Perioperative Management of Mild Hemophilia B During and After Coronary Artery Bypass Grafting: Challenges and Solutions

Rohesh J Fernando; Blaine E Farmer; John G Augoustides; Jeffrey C Gardner; Sean D Johnson; Bao Ha; Jan-Oliver Friess; Markus M Luedi; Gabor Erdoes; Peter J Miller; Caroline Ripat; Michael Fabbro

doi:10.1053/j.jvca.2018.06.005

Perioperative Management of Mild Hemophilia B During and After Coronary Artery Bypass Grafting: Challenges and Solutions

J Cardiothorac Vasc Anesth. 2019 Feb;33(2):549-555. doi: 10.1053/j.jvca.2018.06.005. Epub 2018 Jun 20.

Authors

Affiliations

¹ Cardiothoracic Section, Department of Anesthesiology, Wake Forest School of Medicine, Winston Salem, NC.
² Cardiovascular and Thoracic Section, Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Electronic address: yiandoc@hotmail.com.
³ Cardiovascular and Thoracic Section, Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
⁴ Department of Anesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
⁵ Critical Care Section, Department of Anesthesiology, Wake Forest School of Medicine, Winston Salem, NC; Hematology and Oncology Section, Department of Medicine, Wake Forest School of Medicine, Winston Salem, NC.
⁶ Cardiothoracic Anesthesiology, Department of Anesthesiology, Perioperative Medicine and Pain Management, Miller School of Medicine, University of Miami, Miami, FL.

PMID: 30177475
DOI: 10.1053/j.jvca.2018.06.005

No abstract available

Keywords: World Federation of Hemophilia; bleeding; coronary artery bypass grafting; factor IX; hemophilia B; inhibitors; prothrombin complex concentrate; recombinant factor VIIa.

Publication types

Clinical Conference

MeSH terms

Acute Coronary Syndrome / surgery
Aged
Coronary Artery Bypass*
Factor IX / therapeutic use*
Hemophilia B / complications
Hemophilia B / drug therapy*
Humans
Male
Perioperative Care / methods*
Postoperative Hemorrhage / etiology
Postoperative Hemorrhage / prevention & control*
Recombinant Proteins*

Substances

Recombinant Proteins
Factor IX