Pregnancy and Delivery After PRRT Without Sequelae

Clin Nucl Med. 2018 Nov;43(11):842-845. doi: 10.1097/RLU.0000000000002267.


Peptide receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogues has been proven to be very useful in the management of advanced, well-differentiated neuroendocrine neoplasms (NENs). We present here the pregnancy outcome in a NEN patient, who naturally conceived and gave birth to a healthy baby, after 4 cycles of PRRT administering a cumulative radioactivity of 27.1 GBq. This case underlines that pregnancy and birth without sequelae are possible in patients with NEN who have been treated with PRRT and offers a definitive prospect for patients of reproductive age group who plan conception despite having received or due to undergo PRRT.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Live Birth*
  • Neuroendocrine Tumors / radiotherapy*
  • Pregnancy
  • Radiotherapy / adverse effects*