Social cognition deficits have been observed in individuals at clinical high risk (CHR) for psychosis. Longitudinal change in social cognition were analyzed in CHR individuals from the North American Prodrome Longitudinal Study (NAPLS2) based on outcome at 24 months. Individuals (n = 359) were classified into remission, symptomatic, prodromal progression and transition to psychosis (CHR-T) groups. Social cognition was assessed using theory of mind, emotion perception, and social perception tasks. There were no differences at baseline or 24 months between the groups on social cognition. Non-transition groups improved significantly over time on social cognition, but CHR-T did not show this effect.
Keywords: Clinical high risk; Emotion perception; Psychosis; Social cognition; Social perception; Theory of mind.
Copyright © 2018. Published by Elsevier B.V.
Conflict of interest statement
Conflict of Interest
There are no conflicts of interest for any of the authors with respect to the data in this paper or for the study.
Social Cognition Over Time in Individuals at Clinical High Risk for Psychosis: Findings From the NAPLS-2 CohortD Piskulic et al. Schizophr Res 171 (1-3), 176-81. PMID 26785807.Deficits in social cognition are well established in schizophrenia and have been observed prior to the illness onset. Compared to healthy controls (HCs), individuals at c …
Theory of Mind, Emotion Recognition and Social Perception in Individuals at Clinical High Risk for Psychosis: Findings From the NAPLS-2 CohortM Barbato et al. Schizophr Res Cogn 2 (3), 133-139. PMID 27695675.Social cognition, the mental operations that underlie social interactions, is a major construct to investigate in schizophrenia. Impairments in social cognition are prese …
Age-related Trajectories of Social Cognition in Youth at Clinical High Risk for Psychosis: An Exploratory StudyCA Davidson et al. Schizophr Res 201, 130-136. PMID 29751984.CHR exhibited normal age trajectory for EP, but significantly lower slopes for ToM from age 17 onward. This effect was specific to stimuli exhibiting sarcasm and not to d …
A Developmental Perspective on Social-Cognition Difficulties in Youth at Clinical High Risk for PsychosisSH Lincoln et al. Harv Rev Psychiatry 25 (1), 4-14. PMID 28059932. - ReviewAfter participating in this activity, learners should be better able to:• Evaluate the evolution of social cognitive abilities as a developmental process• Assess the evid …
North American Prodrome Longitudinal Study (NAPLS 2): The Prodromal SymptomsJ Addington et al. J Nerv Ment Dis 203 (5), 328-35. PMID 25919383.In studies describing the long-term follow-up up of youth at clinical high risk (CHR) of psychosis, little attention has been given to details of specific prodromal sympt …
- Barbato M, Liu L, Cadenhead KS, Cannon TD, Cornblatt BA, McGlashan TH, Perkins DO, Seidman LJ, Tsuang MT, Walker EF, Woods SW, Bearden CE, Mathalon DH, Heinssen R, Addington J, 2015. Theory of mind, emotion recognition and social perception in individuals at clinical high risk for psychosis: Findings from the NAPLS-2 cohort. Schizophr. Res. Cogn 2, 133–139. - PMC - PubMed
- Brüne M, Özgürdal S, Ansorge N, von Reventlow HG, Peters S, Nicolas V, Tegenthoff M, Juckel G, Lissek S, 2011. An fMRI study of “theory of mind” in at-risk states of psychosis: Comparison with manifest schizophrenia and healthy controls. Neuroimage 55, 329–337. - PubMed
- Gee DG, Karlsgodt KH, van Erp TGM, Bearden CE, Lieberman MD, Belger A, Perkins DO, Olvet DM, Cornblatt BA, Constable T, Woods SW, Addington J, Cadenhead KS, McGlashan TH, Seidman LJ, Tsuang MT, Walker EF, Cannon TD, 2012. Altered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: A preliminary study. Schizophr. Res 134, 1–9. - PMC - PubMed
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