Wet cupping for hypertension: a systematic review and meta-analysis

Clin Exp Hypertens. 2019;41(5):474-480. doi: 10.1080/10641963.2018.1510939. Epub 2018 Sep 5.


To assess the efficacy and safety of wet cupping in adults with hypertension, we conducted a systematic review and meta-analysis using 13 databases. Wet cupping alone or in combination with antihypertensive medication or acupuncture was used. Seven randomized trials were included, most not of high methodological quality. A few small studies suggested that wet cupping alone versus antihypertensive medication significantly reduced blood pressure and Traditional Chinese Medicine syndrome (hypertension-related symptoms). However based on current evidence, no firm conclusions can be drawn and no clinical recommendations made. Research projects included need validation. Studies indicate that wet cupping is a safe therapy.

Keywords: Wet cupping; effect; hypertension; meta-analysis; systematic review.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Acupuncture Therapy
  • Antihypertensive Agents / therapeutic use
  • Blood Pressure
  • Complementary Therapies / adverse effects
  • Complementary Therapies / methods*
  • Humans
  • Hypertension / therapy*
  • Randomized Controlled Trials as Topic


  • Antihypertensive Agents