Non-infectious diffuse vesiculobullous rash in a pancreas and renal transplant recipient

Transpl Infect Dis. 2018 Dec;20(6):e12990. doi: 10.1111/tid.12990. Epub 2018 Sep 21.

Abstract

Solid organ transplant patients are well established to be at risk of herpes simplex virus and varicella zoster virus infection and reactivation. We present a case of a 41-year-old woman with a history of pancreas and renal transplant who presented with what appeared to be disseminated herpes simplex virus or varicella zoster virus induced rash, but who was ultimately diagnosed and treated as linear IgA bullous dermatosis. This case alerts physicians to other non-infectious dermatoses as a cause of vesiculobullous rash in solid organ transplant patients.

Keywords: dermatitis herpetiformis; disseminated HSV/VZV mimic; linear IgA bullous dermatosis; solid organ transplant.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dermatitis Herpetiformis / diagnosis
  • Diabetes Mellitus, Type 1 / surgery
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunosuppression Therapy / adverse effects*
  • Immunosuppression Therapy / methods
  • Immunosuppressive Agents / adverse effects*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation / adverse effects*
  • Linear IgA Bullous Dermatosis / chemically induced
  • Linear IgA Bullous Dermatosis / diagnosis*
  • Linear IgA Bullous Dermatosis / pathology
  • Pancreas Transplantation / adverse effects*
  • Prednisone / adverse effects
  • Skin / pathology
  • Tacrolimus / adverse effects

Substances

  • Immunosuppressive Agents
  • Prednisone
  • Tacrolimus