Gene regulation by proteins acting nearby and at a distance

Nature. 1986 Aug 21-27;322(6081):697-701. doi: 10.1038/322697a0.

Abstract

Transcription of genes can be controlled by regulatory proteins that bind to sites on the DNA either nearby or at a considerable distance. Recent experiments suggest a unified view of these apparently disparate types of gene regulation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • DNA Helicases / physiology
  • DNA-Binding Proteins / physiology*
  • Fungal Proteins / physiology
  • Gene Expression Regulation*
  • Genes, Regulator
  • Models, Genetic*
  • Nucleic Acid Conformation
  • Operon
  • Protein Binding
  • Protein Conformation
  • Recombination, Genetic
  • Repressor Proteins / physiology
  • Transcription, Genetic*
  • Viral Proteins
  • Viral Regulatory and Accessory Proteins

Substances

  • DNA-Binding Proteins
  • Fungal Proteins
  • Repressor Proteins
  • Viral Proteins
  • Viral Regulatory and Accessory Proteins
  • phage repressor proteins
  • DNA Helicases