Gyrification Needs Correct Sodium Flux!

Neuron. 2018 Sep 5;99(5):867-868. doi: 10.1016/j.neuron.2018.08.005.

Abstract

Channelopathies are disorders that affect the function of ion channels, typically resulting in epilepsy. Smith et al. (2018) discover an unusual association between SCN3A, neuronal migration, and cortical folding, outlining sodium channels as important regulators of brain development.

Publication types

  • Comment

MeSH terms

  • Cerebral Cortex
  • Epilepsy*
  • Humans
  • Ion Channels
  • NAV1.3 Voltage-Gated Sodium Channel
  • Sodium
  • Sodium Channels*

Substances

  • Ion Channels
  • NAV1.3 Voltage-Gated Sodium Channel
  • SCN3A protein, human
  • Sodium Channels
  • Sodium