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Editorial
. 2018 Aug 17;9(64):32276-32277.
doi: 10.18632/oncotarget.25971.

Disabling an oncogenic transcription factor by targeting of control kinases

Christopher R Vakoc  1 , Alex Kentsis  2
Affiliations
Editorial

Disabling an oncogenic transcription factor by targeting of control kinases

Christopher R Vakoc et al. Oncotarget. .
No abstract available

Keywords: kinase; leukemia; therapy; transcription factor.

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Figures

Figure 1
Figure 1. Kinase-dependent dysregulation of MEF2C in acute myeloid leukemia gene expression programs regulating leukemia stem cell maintenance, resistance to apoptosis and chemotherapy resistance
MEF2C is controlled by the MARK and SIK kinases, which can be selectively inhibited using selective tool compound inhibitors HG-9-91-01 and MRT199665.
See this image and copyright information in PMC

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