Levobunolol for the long-term treatment of glaucoma

Gen Pharmacol. 1986;17(4):373-7. doi: 10.1016/0306-3623(86)90177-1.


Systemically, levobunolol is as effective as propranolol for cardiovascular indications, with a greater potency and greater duration of action. Ocularly, levobunolol is as effective and as safe as topical timolol for the long-term treatment of elevated IOP. The utility of topical levobunolol as an additional, effective beta-blocker for the treatment of glaucoma will be determined by additional research and use by ophthalmologists in countries where levobunolol is approved.

Publication types

  • Clinical Trial
  • Review

MeSH terms

  • Airway Resistance / drug effects
  • Animals
  • Clinical Trials as Topic
  • Glaucoma / drug therapy*
  • Heart Diseases / drug therapy
  • Humans
  • Intraocular Pressure / drug effects
  • Kinetics
  • Levobunolol / metabolism
  • Levobunolol / therapeutic use*
  • Levobunolol / toxicity
  • Nervous System / drug effects
  • Receptors, Adrenergic, beta / drug effects
  • Time Factors


  • Receptors, Adrenergic, beta
  • Levobunolol