An innovative dual-phase protocol for pulsed ablative vaginal Erbium:YAG laser treatment of urogynecological symptoms

Eur J Obstet Gynecol Reprod Biol. 2018 Oct:229:167-171. doi: 10.1016/j.ejogrb.2018.08.010. Epub 2018 Sep 3.

Abstract

Objectives: To evaluate a dual-phase protocol for vaginal ablative Erbium:YAG laser treatment in pelvic floor medicine.

Study design: Data from consecutive patients undergoing vaginal Erbium:YAG laser for first-degree pelvic floor complaints at a certified university urogynecological unit were analyzed. Fractional ablative and thermal treatment with adjustable pulse duration, fluence, and pulse interval was performed in single ten-minute treatment course. Followed up interval was 6 weeks including interviews on expectations, goal setting, goal achievement, and satisfaction (EGGS), vaginal pH, and determination of the Gloria-Bachmann-Index (VHI). Post-procedural complications were classified according to definition and classification of the Clavien-Dindo system.

Results: Of 84 patients treated, 71 (21% pre-, 79% post-menopausal) were evaluated. 27% had single urogynecological symptoms, 35% had three or more combined symptoms. Minor post-procedural complications occurred in three patients (CD I, n = 1; CD II, n = 3). The ranges of fluence, determined according to the atrophy state, in the first and second phases were 15-35 and 3-12 J/cm2, respectively. In patients with genitourinary syndrome of menopause, pre- and post-treatment VHI and pH differed significantly [15.3 ± 4.5 vs. 19.9 ± 2.8 (p < 0.001, Student's t test) and 5.2 ± 0.6 vs. 4.8 ± 0.4 (p = 0.024, respectively]. Overall, 82% (n = 58; mean age, 58 ± 12 years) of patients were satisfied with the treatment, 84% (47/56) post-menopausal patients were satisfied.

Conclusions: Vaginal ablative Erbium:YAG laser dual-phase protocol for early urogynecological symptoms was successful and safe, with high patient satisfaction and few, minor complications. Prospective studies are needed to confirm our first data.

Keywords: Clavien-Dindo complication classification; Dual-phase protocol; Pelvic floor medicine; Urogynecology; Vaginal ablative erbium:YAG laser.

MeSH terms

  • Aged
  • Female
  • Gynecologic Surgical Procedures / methods*
  • Humans
  • Lasers, Solid-State / therapeutic use*
  • Middle Aged
  • Pelvic Floor Disorders / surgery*
  • Retrospective Studies