Effect of gatifloxacin in the treatment of ophthalmological diseases and continuous nursing intervention

Pak J Pharm Sci. 2018 Jul;31(4(Special)):1707-1712.


Gatifloxacin is a fourth-generation antibiotic and its antibacterial activity is better. It can play an obvious antiseptic effect in gram-positive bacteria, mycobacterium, mycoplasma, anaerobes and chlamydia. This study analyzed the treatment of the foreign body of the cornea by gatifloxacin eye drops. The results showed that gatifloxacin has a high bacterial clearance rate, which can reach 96.1%. The clinical effect is accurate and the adverse reaction is less. Compared with the control drug levofloxacin, its efficacy and safety were not statistically significant. Moreover, MIC determination of bacteria isolated from the study showed that gatifloxacin had stronger antibacterial activity. At the same time, it can be seen that nursing intervention can effectively improve the satisfaction of the treatment, before the operation, the patient's eye abnormalities, the psychological status of the patient, and the suitability of drug allergy should be evaluated.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / therapeutic use
  • Eye Foreign Bodies / drug therapy*
  • Eye Foreign Bodies / nursing
  • Gatifloxacin / adverse effects
  • Gatifloxacin / therapeutic use*
  • Humans
  • Levofloxacin / adverse effects
  • Levofloxacin / therapeutic use
  • Microbial Sensitivity Tests
  • Middle Aged
  • Ophthalmic Solutions / adverse effects
  • Ophthalmic Solutions / therapeutic use
  • Patient Satisfaction
  • Young Adult


  • Anti-Bacterial Agents
  • Ophthalmic Solutions
  • Levofloxacin
  • Gatifloxacin