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. Apr-Jun 2018;62(2):144-148.

Choroidal Thickness Increase After Micropulse Transscleral Cyclophotocoagulation

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Free PMC article

Choroidal Thickness Increase After Micropulse Transscleral Cyclophotocoagulation

Ramona Barac et al. Rom J Ophthalmol. .
Free PMC article

Abstract

Glaucoma, the affliction that results in optic nerve damage and vision loss, is the main cause of irreversible blindness. The goal of this study was to describe our experience and OCT findings regarding glaucoma patients who underwent MicroPulse Transscleral Cyclophotocoagulation. A variety of glaucoma patients treated with MP-TSCPC were included in our study. LASER settings were 2000mW of 810nm infrared diode micropulse LASER, 31.3% duty cycle and the duration of treatment was between 80-130 s per hemisphere to each eye, at 3 mm of corneoscleral limbus, spearing the nasal and temporal clock hours and also the region with previous filtration surgeries (trabeculectomy). We conducted a prospective study in which twenty-two patients underwent MP-TSCPC under local anaesthesia and they were examined one week, one month, three months, and six months postoperatively. Mean IOP dropped from 35.23 mmHg preoperatively to 17.73mmHg (49.67%) at 1 week follow-up, to 21.81 mmHg (38.09%) at 1 month follow-up, to 22.34 mmHg at 3 months follow-up and to 23.56 mmHg at 6 months follow-up. Four patients (15.8%) underwent a second treatment (at 1 month after the initial treatment) due to insufficient IOP decrease, two of them with success in lowering the IOP postoperatively. By measuring the foveolar choroidal thickness via macular OCT scan, we noticed that all responsive patients had a thicker choroid one week after the laser treatment, with a steady increase of a mean 7.3% that was sustained at one and three months follow-up, while in non-responsive patients, the choroidal thickness remained the same postoperatively, or had a significant decrease. The increase in choroidal thickness in all patients in whom we observed IOP reduction was a significant correlation that supported the mechanism of increased uveoscleral outflow obtained from LASER treatment.

Keywords: choroidal thickness; glaucoma surgery; micropulse; transscleral cyclophotocoagulation.

Figures

Fig. 1
Fig. 1
Series breakdown based on glaucoma type
Fig. 2
Fig. 2
IOP variation before and after MP-TSCPC
Fig. 3
Fig. 3
Number of glaucoma drugs before and after MP-TSCPC
Fig. 4
Fig. 4
Number of acetazolamide doses per day before and after MP-TSCPC
Fig. 5
Fig. 5
Average choroidal thickness before and after MP-TSCPC
Fig. 6
Fig. 6
Choroidal thickness preoperatively
Fig. 7
Fig. 7
Choroidal thickness 1 week postoperatively
Fig. 8
Fig. 8
Choroidal thickness 1 month

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