Peripheral nerve injuries in the pediatric population: a review of the literature. Part III: peripheral nerve tumors in children

Childs Nerv Syst. 2019 Jan;35(1):47-52. doi: 10.1007/s00381-018-3976-6. Epub 2018 Sep 11.


Introduction: Peripheral nerve tumors type, inciedence and treatment in the pediatric population should be analyzed.

Methods: We have performed an extense literature review of this subject.

Results: incidence and distribution are similar to those observed in adults. The most common peripheral nerve tumors in children are neurofibromas and schwannomas. Malignant peripheral nerve sheath tumors are also observed, specially associated with genetic syndromes, like neurofibromatosis and Carney complex.

Conclusion: In this review, peripheral nerve tumors have been divided into three categories to aid with understanding: reactive and hyperplastic lesions, benign tumors, and malignant tumors. The most frequent lesions have been described.

Keywords: Neurofibromas; Pediatric population; Peripheral nerve tumors; Schwannomas.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Neurilemmoma / therapy
  • Neurofibroma / therapy
  • Pediatrics / methods*
  • Peripheral Nerve Injuries / therapy*
  • Peripheral Nervous System Neoplasms / therapy*