Effect of Fluprostenol Isopropyl Ester and 15-Keto Fluprostenol on Eyelash Growth: A Clinical and Pharmacologic Study

Skinmed. 2018 Jul 1;16(4):231-233. eCollection 2018.

Abstract

15-Keto fluprostenol isopropyl ester and 15-keto fluprostenol have demonstrated a stimulatory effect on the growth and thickening of the eyelashes without the disadvantages of the prostaglandin derivatives of the PGF group, which have a hydroxyl group at position 15 in their structure. The two 15-ketoderivatives have the same efficacy as the 15-hydroxyl derivatives in allowing the regrowth, lengthening, darkening, or thickening of the eyelashes, but without darkening the edge of the eyelid or coloring the iris, even temporarily.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Eyelashes / drug effects*
  • Eyelashes / growth & development*
  • Female
  • Humans
  • Luteolytic Agents / pharmacology*
  • Male
  • Middle Aged
  • Prostaglandins F, Synthetic / pharmacology*
  • Young Adult

Substances

  • Luteolytic Agents
  • Prostaglandins F, Synthetic
  • fluprostenol