Eosinopenia and Adverse Outcomes After Clostridium difficile Infections: Of Mice and Men

doi:10.1001/jamasurg.2018.3200

Comment

. 2018 Dec 1;153(12):1133-1134.

doi: 10.1001/jamasurg.2018.3200.

Eosinopenia and Adverse Outcomes After Clostridium difficile Infections: Of Mice and Men

Shuyan Wei^{1

2}, Lillian S Kao^{1

2}

Affiliations

¹ Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston.
² Center for Surgical Trials and Evidence-based Practice, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston.

PMID: 30208383
PMCID: PMC6414281
DOI: 10.1001/jamasurg.2018.3200

Comment

Eosinopenia and Adverse Outcomes After Clostridium difficile Infections: Of Mice and Men

Shuyan Wei et al. JAMA Surg. 2018.

. 2018 Dec 1;153(12):1133-1134.

doi: 10.1001/jamasurg.2018.3200.

Authors

Shuyan Wei^{1

2}, Lillian S Kao^{1

2}

Affiliations

¹ Department of Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston.
² Center for Surgical Trials and Evidence-based Practice, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston.

PMID: 30208383
PMCID: PMC6414281
DOI: 10.1001/jamasurg.2018.3200

No abstract available

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Comment on

Development and Validation of a Prediction Model for Mortality and Adverse Outcomes Among Patients With Peripheral Eosinopenia on Admission for Clostridium difficile Infection.
Kulaylat AS, Buonomo EL, Scully KW, Hollenbeak CS, Cook H, Petri WA Jr, Stewart DB Sr. Kulaylat AS, et al. JAMA Surg. 2018 Dec 1;153(12):1127-1133. doi: 10.1001/jamasurg.2018.3174. JAMA Surg. 2018. PMID: 30208386 Free PMC article.

Cited by

Silent existence of eosinopenia in sepsis: a systematic review and meta-analysis.
Lin Y, Rong J, Zhang Z. Lin Y, et al. BMC Infect Dis. 2021 May 24;21(1):471. doi: 10.1186/s12879-021-06150-3. BMC Infect Dis. 2021. PMID: 34030641 Free PMC article.

References

1. Abou Chakra CN, Pepin J, Valiquette L. Prediction tools for unfavourable outcomes in Clostridium difficile infection: a systematic review. PLoS One. 2012;7(1):e30258. - PMC - PubMed
1. Kulaylat AS, Buonomo EL, Scully KW, et al. Peripheral eosinopenia upon admission associates independently with mortality and outcomes with Clostridium difficile infection JAMA Surg. 2018. (in press). - PMC - PubMed
1. Cowardin CA, Buonomo EL, Saleh MM, et al. The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia. Nat Microbiol. 2016;1(8):16108. - PMC - PubMed
1. Hutton ML, Mackin KE, Chakravorty A, Lyras D. Small animal models for the study of Clostridium difficile disease pathogenesis. FEMS Microbiol Lett. 2014;352(2):140–149. - PubMed
1. Hackam DG, Redelmeier DA. Translation of research evidence from animals to humans. JAMA. 2006;296(14):1731–1732 - PubMed

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[1] Abou Chakra CN, Pepin J, Valiquette L. Prediction tools for unfavourable outcomes in Clostridium difficile infection: a systematic review. PLoS One. 2012;7(1):e30258. - PMC - PubMed

[2] Abou Chakra CN, Pepin J, Valiquette L. Prediction tools for unfavourable outcomes in Clostridium difficile infection: a systematic review. PLoS One. 2012;7(1):e30258. - PMC - PubMed

[3] Kulaylat AS, Buonomo EL, Scully KW, et al. Peripheral eosinopenia upon admission associates independently with mortality and outcomes with Clostridium difficile infection JAMA Surg. 2018. (in press). - PMC - PubMed

[4] Kulaylat AS, Buonomo EL, Scully KW, et al. Peripheral eosinopenia upon admission associates independently with mortality and outcomes with Clostridium difficile infection JAMA Surg. 2018. (in press). - PMC - PubMed

[5] Cowardin CA, Buonomo EL, Saleh MM, et al. The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia. Nat Microbiol. 2016;1(8):16108. - PMC - PubMed

[6] Cowardin CA, Buonomo EL, Saleh MM, et al. The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia. Nat Microbiol. 2016;1(8):16108. - PMC - PubMed

[7] Hutton ML, Mackin KE, Chakravorty A, Lyras D. Small animal models for the study of Clostridium difficile disease pathogenesis. FEMS Microbiol Lett. 2014;352(2):140–149. - PubMed

[8] Hutton ML, Mackin KE, Chakravorty A, Lyras D. Small animal models for the study of Clostridium difficile disease pathogenesis. FEMS Microbiol Lett. 2014;352(2):140–149. - PubMed

[9] Hackam DG, Redelmeier DA. Translation of research evidence from animals to humans. JAMA. 2006;296(14):1731–1732 - PubMed

[10] Hackam DG, Redelmeier DA. Translation of research evidence from animals to humans. JAMA. 2006;296(14):1731–1732 - PubMed

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Eosinopenia and Adverse Outcomes After Clostridium difficile Infections: Of Mice and Men

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Eosinopenia and Adverse Outcomes After Clostridium difficile Infections: Of Mice and Men

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