Nutcracker Syndrome with the Superimposition of Thin Basement Membrane Syndrome

Intern Med. 2019 Feb 1;58(3):411-414. doi: 10.2169/internalmedicine.1433-18. Epub 2018 Sep 12.

Abstract

A 21-year-old woman was referred to our hospital because of proteinuria and hematuria. She had occasional flank pain. A renal biopsy was performed and revealed a thin basement membrane. Therefore, she was diagnosed with thin basement membrane disease. However, the frequency of her flank pain increased. Since her left kidney was slightly larger than the right, nutcracker syndrome (NCS) was suspected. Renal vein ultrasonography and venography were performed, and NCS was confirmed. Her hematuria was multifactorial, and NCS can go unnoticed if there is a comorbidity that also causes hematuria.

Keywords: flank pain; hematuria; left renal vein entrapment; nutcracker syndrome; thin basement membrane disease.

Publication types

  • Case Reports

MeSH terms

  • Basement Membrane / pathology
  • Diagnosis, Differential
  • Female
  • Flank Pain / complications
  • Hematuria / complications
  • Humans
  • Kidney / blood supply
  • Phlebography
  • Proteinuria / complications
  • Renal Nutcracker Syndrome / complications
  • Renal Nutcracker Syndrome / diagnosis*
  • Renal Nutcracker Syndrome / diagnostic imaging
  • Renal Veins / pathology
  • Young Adult