Mesothelial Stem Cells and Stromal Vascular Fraction: Use in Functional Disorders, Wound Healing, Fat Transfer, and Other Conditions

Greg Chernoff; Nathan Bryan; Andrea M Park

doi:10.1016/j.fsc.2018.06.009

Mesothelial Stem Cells and Stromal Vascular Fraction: Use in Functional Disorders, Wound Healing, Fat Transfer, and Other Conditions

Facial Plast Surg Clin North Am. 2018 Nov;26(4):487-501. doi: 10.1016/j.fsc.2018.06.009. Epub 2018 Aug 16.

Authors

Greg Chernoff¹, Nathan Bryan², Andrea M Park³

Affiliations

¹ Chernoff Cosmetic Surgeons, Private Practice, 9002 N Meridian Street, Suite 205, Indianapolis, IN 46260, USA; Chernoff Cosmetic Surgeons, Private Practice, 1701 4th Street, Suite 100, Santa Rosa, CA 95404, USA; Chernoff Cosmetic Surgeons, Private Practice, 17 Wenjiing Road, Weiyang, Xian 710032, China. Electronic address: greg@drchernoff.com.
² Department of Molecular and Human Genetics, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.
³ UCLA Department of Otolaryngology Head and Neck Surgery, Facial Plastic Surgery, 200 UCLA Medical Plaza, Suite 500, Los Angeles, CA 90095, USA.

PMID: 30213429
DOI: 10.1016/j.fsc.2018.06.009

Abstract

Autologous human fat-derived mesenchymal stem cells are present in stromal vascular fraction. Stromal vascular fraction can be easily and safely extracted from lipoaspirate. The regenerative, antiinflammatory and immunomodulatory effects of stromal vascular fraction are being documented in ongoing therapeutic response studies.

Keywords: Adipose-derived stem cells; Cellular therapy; Nitric oxide; Stromal vascular fraction.

Publication types

Review

MeSH terms

Acne Vulgaris / therapy
Adipose Tissue / transplantation*
Humans
Leg Ulcer / therapy
Mesenchymal Stem Cell Transplantation*
Mesenchymal Stem Cells*
Nitric Oxide / metabolism
Wound Healing*

Substances

Nitric Oxide