Phase Separation in Biology and Disease

doi:10.1016/j.jmb.2018.09.006

Editorial

. 2018 Nov 2;430(23):4603-4606.

doi: 10.1016/j.jmb.2018.09.006. Epub 2018 Sep 11.

Phase Separation in Biology and Disease

Julie D Forman-Kay¹, Richard W Kriwacki², Geraldine Seydoux³

Affiliations

¹ Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: forman@sickkids.ca.
² Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA. Electronic address: richard.kriwacki@stjude.org.
³ Department of Molecular Biology and Genetics, HHMI, School of Medicine, Johns Hopkins University, 725 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: gseydoux@jhmi.edu.

PMID: 30213727
PMCID: PMC6779308
DOI: 10.1016/j.jmb.2018.09.006

Free PMC article

Editorial

Phase Separation in Biology and Disease

Julie D Forman-Kay et al. J Mol Biol. 2018.

Free PMC article

. 2018 Nov 2;430(23):4603-4606.

doi: 10.1016/j.jmb.2018.09.006. Epub 2018 Sep 11.

Authors

Julie D Forman-Kay¹, Richard W Kriwacki², Geraldine Seydoux³

Affiliations

¹ Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: forman@sickkids.ca.
² Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA. Electronic address: richard.kriwacki@stjude.org.
³ Department of Molecular Biology and Genetics, HHMI, School of Medicine, Johns Hopkins University, 725 N. Wolfe Street, Baltimore, MD 21205, USA. Electronic address: gseydoux@jhmi.edu.

PMID: 30213727
PMCID: PMC6779308
DOI: 10.1016/j.jmb.2018.09.006

No abstract available

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References

1. Wilson E, The structure of protoplasm, Science 10 (1899) 33–45, 10.1126/science.10.237.33. - DOI - PubMed
1. Deryusheva S, Gall JG, Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle, Proc. Natl. Acad. Sci. U. S. A 101 (2004) 4810–4814, 10.1073/pnas.0401106101. - DOI - PMC - PubMed
1. Handwerger KE, Murphy C, Gall JG, Steady-state dynamics of Cajal body components in the Xenopus germinal vesicle,J. Cell Biol 160 (2003) 495–504, 10.1083/jcb.200212024. - DOI - PMC - PubMed
1. Brangwynne CP, Eckmann CR, Courson DS, Rybarska A,Hoege C, Gharakhani J, Jülicher F, Hyman AA, Germline P granules are liquid droplets that localize by controlled dissolution/condensation, Science 324 (2009) 1729–1732, 10.1126/science.1172046. - DOI - PubMed
1. Brangwynne CP, Mitchison TJ, Hyman AA, Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes, Proc. Natl. Acad. Sci 108 (2011) 4334–4339, 10.1073/pnas.1017150108. - DOI - PMC - PubMed

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[1] Wilson E, The structure of protoplasm, Science 10 (1899) 33–45, 10.1126/science.10.237.33. - DOI - PubMed

[2] Wilson E, The structure of protoplasm, Science 10 (1899) 33–45, 10.1126/science.10.237.33. - DOI - PubMed

[3] Deryusheva S, Gall JG, Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle, Proc. Natl. Acad. Sci. U. S. A 101 (2004) 4810–4814, 10.1073/pnas.0401106101. - DOI - PMC - PubMed

[4] Deryusheva S, Gall JG, Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle, Proc. Natl. Acad. Sci. U. S. A 101 (2004) 4810–4814, 10.1073/pnas.0401106101. - DOI - PMC - PubMed

[5] Handwerger KE, Murphy C, Gall JG, Steady-state dynamics of Cajal body components in the Xenopus germinal vesicle,J. Cell Biol 160 (2003) 495–504, 10.1083/jcb.200212024. - DOI - PMC - PubMed

[6] Handwerger KE, Murphy C, Gall JG, Steady-state dynamics of Cajal body components in the Xenopus germinal vesicle,J. Cell Biol 160 (2003) 495–504, 10.1083/jcb.200212024. - DOI - PMC - PubMed

[7] Brangwynne CP, Eckmann CR, Courson DS, Rybarska A,Hoege C, Gharakhani J, Jülicher F, Hyman AA, Germline P granules are liquid droplets that localize by controlled dissolution/condensation, Science 324 (2009) 1729–1732, 10.1126/science.1172046. - DOI - PubMed

[8] Brangwynne CP, Eckmann CR, Courson DS, Rybarska A,Hoege C, Gharakhani J, Jülicher F, Hyman AA, Germline P granules are liquid droplets that localize by controlled dissolution/condensation, Science 324 (2009) 1729–1732, 10.1126/science.1172046. - DOI - PubMed

[9] Brangwynne CP, Mitchison TJ, Hyman AA, Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes, Proc. Natl. Acad. Sci 108 (2011) 4334–4339, 10.1073/pnas.1017150108. - DOI - PMC - PubMed

[10] Brangwynne CP, Mitchison TJ, Hyman AA, Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes, Proc. Natl. Acad. Sci 108 (2011) 4334–4339, 10.1073/pnas.1017150108. - DOI - PMC - PubMed

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Phase Separation in Biology and Disease

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Phase Separation in Biology and Disease

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