Peripheral nerve injuries in the pediatric population: a review of the literature. Part I: traumatic nerve injuries

Childs Nerv Syst. 2019 Jan;35(1):29-35. doi: 10.1007/s00381-018-3974-8. Epub 2018 Sep 13.


Objective: This article reviews the clinical results that can be obtained after repair of a traumatic peripheral nerve injury in the pediatric population.

Methods: A systematic review of the published literature has been made.

Results: Functional outcome after major nerve injuries is sometimes disappointing in adults. However, children have been reported to experience much better functional results after nerve repair than adults. Moreover, recovery generally is faster in children. The superior capacity of children's central nervous system to adapt to external or internal environmental changes (neural plasticity) and the shorter recovery distance from the axon repair site to the target muscle are claimed to be crucial determinants of their favorable outcomes. Moreover, even in the pediatric population, it has been demonstrated that functional results are better the younger the patient is, including better clinical results in those injured in early childhood (< 6 years old) than in those injured in adolescence. Other favorable prognostic factors include the type of nerve injury (with complete transections doing less well than crush injuries) and the timing of surgery (with better outcomes after early repairs).

Conclusions: All efforts should be done to repair in a timely and adequate fashion traumatic peripheral nerve injuries in children, as the results are good.

Keywords: Nerve section; Pediatric patients; Peripheral nerve injury; Traumatic nerve lesion.

Publication types

  • Systematic Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Neurosurgical Procedures
  • Pediatrics / methods*
  • Peripheral Nerve Injuries / pathology
  • Peripheral Nerve Injuries / surgery
  • Peripheral Nerve Injuries / therapy*
  • Trauma, Nervous System / pathology
  • Trauma, Nervous System / surgery
  • Trauma, Nervous System / therapy*
  • Treatment Outcome