It is repeatedly advocated in the medical literature the need of reshaping the care process in order to better address the unmet clinical needs of the highly vulnerable and complex ageing population. In the past twenty years, frailty has assumed the role of an arising and independent geriatric condition, different from disability and multimorbidity. Frailty is highly prevalent in older persons. The proper management of frailty relies on the accurate collection and interpretation of a wide spectrum of information about the health status of the individual. However, the optimal intervention plan cannot be correctly designed and implemented without the evaluation of the social characteristics of the frail older person. Unfortunately, this aspect has frequently been overlooked and research is still lagging on the topic. The main scope of this review is to present current evidence and propose possible axes of investigation in this field.