Treatment Response in Sympathetic Ophthalmia as Assessed by Widefield OCT Angiography

Ophthalmic Surg Lasers Imaging Retina. 2018 Sep 1;49(9):726-730. doi: 10.3928/23258160-20180831-13.

Abstract

The authors report the widefield montage swept-source optical coherence tomography angiography (OCTA) findings in a 36-year-old male with sympathetic ophthalmia and illustrate the presence of multiple small areas of choriocapillaris flow voids that likely correspond to areas of choriocapillaris ischemia. Using sequential imaging, the authors observed that these flow voids improved following initiating of steroid and immunosuppressive therapy and almost completely resolved following 6 months of therapy with corresponding improvement in visual acuity. This report highlights the role of widefield montage OCTA to detect these likely ischemic changes within the choriocapillaris in sympathetic ophthalmia and demonstrates that they can be used as an anatomic marker to monitor treatment response. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:726-730.].

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Choroid / pathology*
  • Choroid Diseases / diagnosis*
  • Choroid Diseases / drug therapy
  • Choroid Diseases / etiology
  • Fluorescein Angiography / methods*
  • Follow-Up Studies
  • Fundus Oculi
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Ophthalmia, Sympathetic / complications
  • Ophthalmia, Sympathetic / diagnosis
  • Ophthalmia, Sympathetic / drug therapy*
  • Retinal Vessels / pathology*
  • Tomography, Optical Coherence / methods*
  • Visual Acuity*

Substances

  • Immunosuppressive Agents