Natural history of Klüver-Bucy syndrome after treated herpes encephalitis

South Med J. 1986 Nov;79(11):1376-8. doi: 10.1097/00007611-198611000-00014.


We present the natural history of three patients with features of Klüver-Bucy syndrome after treated herpes encephalitis. Although cognitive and behavioral disturbances following herpes encephalitis are often severe, improvement can occur over an extended period, and chronic residual sequelae may be relatively mild. The pattern of memory impairment is consistent with the current hypothesis that medial temporal lobe structures mediate memory consolidation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cognition Disorders / etiology*
  • Encephalitis / complications*
  • Encephalitis / drug therapy
  • Female
  • Herpesviridae Infections / complications*
  • Herpesviridae Infections / drug therapy
  • Humans
  • Male
  • Prognosis
  • Sexual Behavior*
  • Syndrome