Effectiveness of Intraductal Meibomian Gland Probing in Addition to the Conventional Treatment in Patients with Obstructive Meibomian Gland Dysfunction

Ocul Immunol Inflamm. 2019;27(8):1345-1351. doi: 10.1080/09273948.2018.1522357. Epub 2018 Sep 20.

Abstract

Purpose: To evaluate the effectiveness of intraductal meibomian gland probing in addition to conventional treatment for the management of obstructive meibomian gland dysfunction (O-MGD).Methods: Totally, 40 patients were divided into two groups to receive either conventional treatment alone (group 1: 40 eyes of 20 patients) or conventional treatment plus probing (group 2: 40 eyes of 20 patients). The ocular surface disease index score, Schirmer 1 test, tear film break-up time, Oxford grading of ocular surface, meibum expressibility, and quality scores were evaluated baseline and compared with the end of treatment (day 30 and day 90).Results: There was no significant difference in baseline scores between groups (All p > 0.05). All scores demonstrated significantly improvement from baseline in both group, and it was faster in group 2 (All p < 0.05).Conclusion: This study showed that intraductal meibomian gland probing seems to provide rapid symptom relief and clinical improvement for patients with O-MGD.

Keywords: Conventional treatment; OSDI score; intraductal meibomian gland probing; obstructive meibomian gland dysfunction; rapid symptom relief.

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Conservative Treatment / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Massage / methods
  • Meibomian Gland Dysfunction / therapy*
  • Meibomian Glands / surgery*
  • Middle Aged
  • Ophthalmic Solutions
  • Ophthalmologic Surgical Procedures / methods*
  • Punctures
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Ophthalmic Solutions