Peripheral Kappa Opioid Receptor Signaling Takes on a Central Role

Neuron. 2018 Sep 19;99(6):1102-1104. doi: 10.1016/j.neuron.2018.09.006.


With the current unmet demand for effective analgesics and the opioid crisis, pain relief without major central adverse effects is highly appealing. In this issue of Neuron, Snyder et al. (2018) report on the localization, functions, and therapeutic potential of kappa opioid receptors in peripheral sensory neurons.

Publication types

  • Comment

MeSH terms

  • Analgesics*
  • Analgesics, Opioid
  • Receptors, Opioid, kappa*
  • Sensory Receptor Cells
  • Signal Transduction / drug effects


  • Analgesics
  • Analgesics, Opioid
  • Receptors, Opioid, kappa