Recurrent Merkel cell carcinoma of the gluteal region: A case report

Dermatol Ther. 2019 Jan;32(1):e12749. doi: 10.1111/dth.12749. Epub 2018 Oct 11.

Abstract

Merkel cell carcinoma (MCC) is a rare malignant tumor of the skin. The development of MCC on non-sun-exposed skin is extremely rare, with few cases reported in the literature. The present authors aimed to highlight the characteristic features and treatment options of this tumor. The present authors present a 50-year-old man who developed MCC on the left gluteal region (non-sun-exposed skin). After surgery with clear margins, adjuvant radiotherapy was given. Three months after radiotherapy, lymphatic recurrence was observed and he was treated with chemotherapy. On follow-up, systemic metastases were found and palliative treatment was planned.

Keywords: Merkel cell carcinoma; chemotherapy; non-sun-exposed; radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biopsy
  • Buttocks
  • Carcinoma, Merkel Cell / chemistry
  • Carcinoma, Merkel Cell / diagnostic imaging
  • Carcinoma, Merkel Cell / secondary*
  • Carcinoma, Merkel Cell / therapy
  • Humans
  • Immunohistochemistry
  • Lymph Nodes / chemistry
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis
  • Male
  • Margins of Excision
  • Middle Aged
  • Palliative Care
  • Positron Emission Tomography Computed Tomography
  • Radiotherapy, Adjuvant
  • Skin Neoplasms / chemistry
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / therapy
  • Treatment Outcome

Substances

  • Biomarkers, Tumor