Acid Peptic Disease

Surg Clin North Am. 2018 Oct;98(5):933-944. doi: 10.1016/j.suc.2018.06.003.


The management of peptic ulcer disease has radically changed over the last 40 years from primarily surgical treatment to medical therapy nearly eliminating the need for elective surgery in these patients. Although there has been a decline in patients requiring acute surgical intervention for complications of peptic ulcer disease (perforation, bleeding, and obstruction), these patients still make up a significant proportion of hospital admissions every year. The modern acute care surgeon must have significant knowledge of the multiple treatment modalities used to appropriately care for these patients.

Keywords: Bleeding ulcer; Helicobacter pylori; Obstructing ulcer; Peptic ulcer disease; Perforated ulcer.

Publication types

  • Review

MeSH terms

  • Helicobacter Infections / complications
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / therapy
  • Helicobacter pylori
  • Humans
  • Peptic Ulcer / diagnosis
  • Peptic Ulcer / etiology*
  • Peptic Ulcer / therapy*