A novel method to quantify arterial pulse waveform morphology: attractor reconstruction for physiologists and clinicians

Physiol Meas. 2018 Oct 30;39(10):104008. doi: 10.1088/1361-6579/aae46a.

Abstract

Current arterial pulse monitoring systems capture data at high frequencies (100-1000 Hz). However, they typically report averaged or low frequency summary data such as heart rate and systolic, mean and diastolic blood pressure. In doing so, a potential wealth of information contained in the high-fidelity waveform data is discarded, data which has long been known to contain useful information on cardiovascular performance. Here we summarise a new mathematical method, attractor reconstruction, which enables the quantification of arterial waveform shape and variability in real-time. The method can handle long streams of non-stationary data and does not require preprocessing of the raw physiological data by the end user. Whilst the detailed mathematical proofs have been described elsewhere (Aston et al 2008 Physiol. Meas. 39), the authors were motivated to write a summary of the method and its potential utility for biomedical researchers, physiologists and clinician readers. Here we illustrate how this new method may supplement and potentially enhance the sensitivity of detecting cardiovascular disturbances, to aid with biomedical research and clinical decision making.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cardiovascular Diseases / diagnosis*
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / therapy
  • Diagnosis, Computer-Assisted / methods
  • Humans
  • Pulse Wave Analysis / methods*
  • Sensitivity and Specificity