A pendant peptide endows a sunscreen with water-resistance

Org Biomol Chem. 2018 Oct 10;16(39):7139-7142. doi: 10.1039/c8ob01773e.


Ultraviolet light causes skin cancer. Salicylic acid and other molecular filters absorb damaging radiation but are washed away readily. Conjugation to a collagen mimetic peptide is shown to retain salicylic acid on collagen-containing skin surrogates after repeated washing. This strategy, which is highly modular, could enhance the water-resistance of sunscreens.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Collagen / chemistry
  • Peptidomimetics / chemistry*
  • Sunscreening Agents / chemistry*
  • Surface Properties
  • Water / chemistry*


  • Peptidomimetics
  • Sunscreening Agents
  • Water
  • Collagen