Prototyping a precision oncology 3.0 rapid learning platform

BMC Bioinformatics. 2018 Sep 26;19(1):341. doi: 10.1186/s12859-018-2374-0.


Background: We describe a prototype implementation of a platform that could underlie a Precision Oncology Rapid Learning system.

Results: We describe the prototype platform, and examine some important issues and details. In the Appendix we provide a complete walk-through of the prototype platform.

Conclusions: The design choices made in this implementation rest upon ten constitutive hypotheses, which, taken together, define a particular view of how a rapid learning medical platform might be defined, organized, and implemented.

Keywords: Controlled natural language; Nanopublication; Natural language processing; Precision oncology; Rapid learning; Targeted therapies; Treatment reasoning; Tumor boards.

MeSH terms

  • Algorithms
  • Education, Medical
  • Humans
  • Medical Oncology*
  • Precision Medicine*
  • Publications
  • Software*