The princess and the p-value: A case report of suspected autoimmune encephalitis and functional neurological disorder in a pediatric patient

Appl Neuropsychol Child. 2020 Jan-Mar;9(1):13-20. doi: 10.1080/21622965.2018.1501373. Epub 2018 Sep 28.

Abstract

Autoimmune encephalitis is a rapidly evolving area of study in pediatric populations, and functional neurological symptom disorders are under-studied in children. Differential diagnosis among these disorders is challenging, but pediatric neuropsychologists are uniquely qualified to assist a multidisciplinary team. This case illustrates a young girl with suspected autoimmune encephalitis, whose symptoms were revealed to be primarily functional in nature. She was followed over the course of two years with neuropsychological evaluation and consultation. Immunomodulatory treatments were tried, but psychosocial interventions eventually had the greatest impact. The implications for careful monitoring and assessment of pediatric patients with suspected autoimmune encephalitis by a pediatric neuropsychologist are illuminated by the case of this interesting girl and her family.

Keywords: Autoimmune encephalitis in children; conversion disorder; functional neurological disorder; neuroimmunology.

Publication types

  • Case Reports

MeSH terms

  • Autoimmune Diseases of the Nervous System / diagnosis*
  • Child
  • Conversion Disorder / diagnosis*
  • Diagnosis, Differential
  • Encephalitis / diagnosis*
  • Female
  • Humans
  • Nervous System Diseases / diagnosis*
  • Neuropsychological Tests