Prevalence of oropharyngeal group B Streptococcus colonization in mothers, family, and health care providers

PLoS One. 2018 Sep 28;13(9):e0204617. doi: 10.1371/journal.pone.0204617. eCollection 2018.

Abstract

Objective: To determine the prevalence and serotype of oropharyngeal Group B Streptococcal (GBS) colonization of mothers, their family & friends, and health care providers of recently delivered patients as a potential reservoir of neonatal exposure to GBS.

Methods: This is a prospective, single-center observational study of: (1) patients, (2) their family and friends, and (3) health care providers all of whom may come in close contact with neonates. Oropharyngeal GBS colonization and serotype was determined.

Results: Three hundred and seventy three samples were collected. The prevalence of oropharyngeal GBS colonization among all study participants was 23.1% (N = 86). The most commonly found serotypes were 1b (12.8%, N = 11), III (27.9%, N = 24), and V (17.4%, N = 15). The prevalence of oropharyngeal GBS colonization among mothers was 26% (N = 31/121), 22% (N = 39/178) in family and friends, and 21.6% (N = 16/74) in health care providers.

Conclusion: Group B Streptococcus colonizes the oropharynx in 1 in 5 mothers, family and friends, and health care providers who come in direct contact with neonates. Further research is needed to determine if this potential reservoir for neonatal exposure could lead to early or late onset neonatal GBS colonization or infection.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Carrier State / epidemiology*
  • Cross-Sectional Studies
  • Family
  • Female
  • Friends
  • Health Personnel
  • Humans
  • Infant, Newborn
  • Male
  • Mothers
  • Oropharynx / microbiology*
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Prevalence
  • Prospective Studies
  • Serogroup
  • Streptococcal Infections / epidemiology*
  • Streptococcus agalactiae / classification
  • Streptococcus agalactiae / isolation & purification*
  • Young Adult

Grants and funding

Laboratory analysis of Group B Streptococcal cultures and serotyping was paid for by the Department of Women’s Health, Arrowhead Regional Medical Center. No other sources of funding were received. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.