Effect of age factors on health-related quality of life in patients with lower rectal cancer after sphincter-saving surgery: A 1-year longitudinal study

Yumiko Kinoshita; Rieko Izukura; Mami Miyazono; Shuntaro Nagai; Eiji Oki; Maki Kanaoka; Hisako Nakao; Akiko Chishaki; Ryuichi Mibu

doi:10.1016/j.archger.2018.09.004

Effect of age factors on health-related quality of life in patients with lower rectal cancer after sphincter-saving surgery: A 1-year longitudinal study

Arch Gerontol Geriatr. 2018 Nov-Dec:79:185-191. doi: 10.1016/j.archger.2018.09.004. Epub 2018 Sep 12.

Authors

Yumiko Kinoshita¹, Rieko Izukura², Mami Miyazono³, Shuntaro Nagai⁴, Eiji Oki⁵, Maki Kanaoka⁶, Hisako Nakao⁷, Akiko Chishaki⁸, Ryuichi Mibu⁹

Affiliations

¹ Department of Health Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: kino@med.kyushu-u.ac.jp.
² Medical Information Center, Kyushu University Hospital, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: ochamame@info.med.kyushu-u.ac.jp.
³ Department of Health Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Department of Nursing, Fukuoka Nursing College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan. Electronic address: miyazonom@college.fdcnet.ac.jp.
⁴ Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: shuntaro@surg1.med.kyushu-u.ac.jp.
⁵ Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: okieiji@surg2.med.kyushu-u.ac.jp.
⁶ Department of Nursing, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahata-nishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan. Electronic address: kanaoka@health.uoeh-u.ac.jp.
⁷ Department of Health Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: hnakao@med.kyushu-u.ac.jp.
⁸ Department of Health Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: chishaki@hs.med.kyushu-u.ac.jp.
⁹ Department of Health Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: mibur@jcom.home.ne.jp.

PMID: 30269003
DOI: 10.1016/j.archger.2018.09.004

Abstract

Purpose: To examine age-related factors influencing health-related quality of life (HR-QOL) among patients with lower rectal cancer during the 12-month period after sphincter-saving surgery (SSS).

Material and methods: In this 1-year longitudinal study, 137 patients (120 patients completed, and 82 aged ≥60 years) answered the European Organization for Research and Treatment of Cancer questionnaire (EORTC-C30/CR38) assessing their HR-QOL and related factors during the 12 months after SSS.

Results: No significant differences in HR-QOL were found before surgery. Only among those aged ≥60 years, global health status/QOL and cognitive functioning showed a significant decrease one month after surgery. At one month after SSS, the role functioning of groups <60 years old (which is negatively related to defecation problems, insomnia, and financial difficulties) was lower compared to those aged ≥60 years; and role functioning was significantly related to global health status/QOL. Six months after SSS, the global health status/QOL had recovered. In both groups, global health status/QOL was related to role and social functioning. Among participants aged <60 years, global health status/QOL was significantly related to emotional functioning, which is related to future perspective. Among participants aged ≥60 years only, global health status/QOL was significantly related to cognitive functioning; pain, financial difficulties, and defecation problems negatively influenced HR-QOL. Symptoms specific after SSS: defecation problems (in both group), micturition problems (only ≥60 years), and sexual problems (only<60 years) influenced HR-QOL.

Conclusion: Health care providers should assess the influence of age-related factors during the early post-operative period after SSS to improve HR-QOL.

Keywords: Age factor; Prospective study; Quality of life; Rectal neoplasm; Sphincter-saving surgery; Symptom.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Age Factors
Aged
Female
Health Status*
Humans
Japan
Longitudinal Studies
Male
Middle Aged
Quality of Life*
Rectal Neoplasms / surgery*