Clinical evidence on haemodiafiltration

Nephrol Dial Transplant. 2018 Oct 1;33(suppl_3):iii53-iii58. doi: 10.1093/ndt/gfy218.

Abstract

Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Hemodiafiltration / methods*
  • Hemodiafiltration / standards*
  • Humans
  • Kidney Failure, Chronic / therapy*
  • Membranes, Artificial*
  • Renal Dialysis / methods*
  • Renal Dialysis / standards*

Substances

  • Membranes, Artificial