ABO blood group and the risk of lung cancer in Greek adults: a case - control study

Exp Oncol. 2018 Oct;40(3):249-250.

Abstract

Aim: The present study aimed to investigate any possible association between ABO blood groups and lung cancer.

Materials and methods: The study was conducted on 122 lung cancer patients and 1,255 matched-healthy individuals that were reviewed retrospectively. Chi-square and logistic regression models were used for statistical analysis.

Results: No significant difference between lung cancer patients and the control group was recorded regarding ABO blood types and the risk of lung cancer (p = 0.055, OR = 0.79, 95% CI 0.61-1.03). Male gender (p = 0.006, OR = 2.08, 95% CI 1.24-3.49) and smoking (p = 0.000, OR = 3.13, 95% CI 1.72-5.69) were significantly associated with the risk of lung cancer.

Conclusion: No association between ABO blood types and the risk of lung cancer was observed.

MeSH terms

  • ABO Blood-Group System / genetics*
  • Aged
  • Blood Group Antigens / genetics
  • Female
  • Genetic Association Studies
  • Genetic Predisposition to Disease*
  • Greece
  • Humans
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Risk Factors
  • Sex Factors
  • Smoking / genetics
  • Smoking / pathology

Substances

  • ABO Blood-Group System
  • Blood Group Antigens