[Blue toe syndrome as a clinical finding of pheochromocytoma]

Medicina (B Aires). 2018;78(5):368-371.
[Article in Spanish]


Pheochromocytomas are tumors that arise from chromaffin cells of the sympathetic nervous system and act by synthesizing and releasing catecholamines. They usually occur between the fourth and fifth decade of life and have a very wide clinical presentation. They occur only in 0.1-0.2% of the hypertensive population and represent a treatable and curable cause of arterial hypertension, as well as other symptoms derived from the uncontrolled secretion of catecholamines. Peripheral arterial ischemia secondary to massive amines release by a pheochromocytoma is a very uncommon condition. Here we report a case of pheochromocytoma manifested as blue finger syndrome in a patient with palpable distal pulses and history of poor blood pressure control despite treatment with two drugs.

Keywords: blue toe syndrome; catecholamines; digital necrosis; hypertensive crises; pheochromocytoma.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / complications*
  • Adrenal Gland Neoplasms / diagnostic imaging
  • Adrenal Gland Neoplasms / pathology
  • Blue Toe Syndrome / etiology*
  • Blue Toe Syndrome / pathology
  • Computed Tomography Angiography / methods
  • Humans
  • Male
  • Middle Aged
  • Necrosis
  • Pheochromocytoma / complications*
  • Pheochromocytoma / diagnostic imaging
  • Pheochromocytoma / pathology