TFG-RARA: A novel fusion gene in acute promyelocytic leukemia that is responsive to all-trans retinoic acid

Leuk Res. 2018 Nov:74:51-54. doi: 10.1016/j.leukres.2018.09.012. Epub 2018 Sep 29.

Authors

Mei-Ling Chong¹, Hao Cheng¹, Peisong Xu¹, Hong You¹, Min Wang¹, Lu Wang², Hao-Han Ho³

Affiliations

¹ Veritas Genetics, Danvers, MA, USA.
² Department of Pathology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: lu.wang2@stjude.org.
³ Veritas Genetics, Danvers, MA, USA; Department of Molecular Pathology, PathGroup, Nashville, TN, USA. Electronic address: hho@pathgroup.com.

PMID: 30292835
DOI: 10.1016/j.leukres.2018.09.012

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adolescent
Humans
Leukemia, Promyelocytic, Acute* / drug therapy
Leukemia, Promyelocytic, Acute* / genetics
Leukemia, Promyelocytic, Acute* / metabolism
Leukemia, Promyelocytic, Acute* / pathology
Male
Oncogene Proteins, Fusion* / genetics
Oncogene Proteins, Fusion* / metabolism
Proteins* / genetics
Proteins* / metabolism
Retinoic Acid Receptor alpha* / genetics
Retinoic Acid Receptor alpha* / metabolism
Tretinoin / administration & dosage*
Vesicular Transport Proteins

Substances

Oncogene Proteins, Fusion
Proteins
Retinoic Acid Receptor alpha
Tretinoin
RARA protein, human
TFG protein, human
Vesicular Transport Proteins