Objective: Regurgitation, infantile colic, and functional constipation are common gastrointestinal symptoms in childhood, the aim of this study was to explore the prevalence and distribution of these symptoms in China. Methods: A screening program in infants aged 0 to 3 years selected through stratified cluster random sampling was carried out in 7 cities in China. Questionnaires were filled, and then diagnosis were made according to Rome Ⅳ criteria. Areas, (urban-rural), age and gender distribution of prevalence of childhood common gastrointestinal symptoms were analyzed. Results: Totally, 20 932 effective questionnaires were returned. The total number of infants aged 0 to 1 years was 10 193. Regurgitation was diagnosed in 1 960 infants, with the prevalence of 19.2%, among infants aged 0 to 3 months that had highest prevalence (29.8%). The prevalence decreased with age, and differences among different age groups showed significant. For infantile colic, 4 470 infants aged 0 to 5 months were analyzed and the prevalence of infantile colic was 7.3%. The prevalence of infantile colic was the highest in infants aged 1 to 2 months (10.0%). Age specific difference was significant. Of all the infants, functional constipation was diagnosed in 1 755 infants with the prevalence of 8.4%, and the lowest prevalence was found in infants aged 0 to 3 months (6.2%), and the highest prevalence was in infants aged 30 to 36 months (10.0%). The differences in different age group were significant. Conclusion: Symptoms of regurgitation, infantile colic, and functional constipation are common in infants in China, with age specific difference in prevalence of the symptoms.
目的： 对中国7个城市0~3岁婴幼儿常见的胃肠道不适症状进行现况调查，探讨婴幼儿常见胃肠道不适症状的患病率和流行病学特征。 方法： 应用分层、整群随机抽样方法对中国7城市0~3岁常住婴幼儿进行问卷调查，根据调查结果，按国际通用的婴幼儿功能性胃肠病Rome Ⅳ诊断标准判断常见胃肠道不适症状的患病率，并分析其地域、城乡、年龄和性别分布特征。 结果： 共回收有效问卷20 932份。0~1岁婴儿共10 193人，出现反流者共1 960人，患病率为19.2%，0~3月龄婴儿反流的患病率最高（29.8%），之后随年龄增加逐渐降低，不同年龄组间差异有统计学意义。0~5月龄婴儿共4 470人，出现肠绞痛者共325人，患病率为7.3%，1~2月龄婴儿肠绞痛的患病率最高（10.0%），不同年龄组婴儿肠绞痛的患病率差异有统计学意义。在0~3岁婴幼儿中，功能性便秘者1 755人，患病率为8.4%，0~3月龄婴儿患病率最低（6.2%），30~36月龄婴儿患病率最高（10.0%），不同年龄组间便秘的患病率差异有统计学意义。 结论： 反流、肠绞痛、功能性便秘等胃肠道症状在健康婴幼儿中普遍存在，患病率有明显的年龄差异特点。.
Keywords: Constipation; Epidemiology; Gastrointestinal symptom; Infantile colic; Infants; Regurgitation.