Cardiovascular effects of caffeinated beverages

Trends Cardiovasc Med. 2019 Aug;29(6):345-350. doi: 10.1016/j.tcm.2018.09.019. Epub 2018 Oct 4.


Caffeine is the world's most popular 'drug', with tea and coffee a ubiquitous part of daily life. As a psychoactive stimulant, there are potential concerns regarding adverse cardiovascular squeal. Cardiovascular conditions, encompassing hypertension, coronary artery disease, rhythm disorders and heart failure affect billions of patients worldwide. We aim to provide a patient-centered comprehensive review of the cardiovascular effects of caffeinated beverages as they pertain to various common cardiovascular conditions. We conclude that intake of tea and coffee, particularly in moderate doses, does not appear to be harmful and may even be beneficial in a range of cardiovascular conditions, including coronary artery disease, heart failure and arrhythmias.

Keywords: Atrial fibrillation; Caffeine; Coffee; Coronary artery disease; Hypertension; Tea.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Administration, Oral
  • Animals
  • Caffeine / administration & dosage*
  • Caffeine / adverse effects
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / prevention & control
  • Cardiovascular System / drug effects*
  • Cardiovascular System / physiopathology
  • Central Nervous System Stimulants / administration & dosage*
  • Central Nervous System Stimulants / adverse effects
  • Coffee* / adverse effects
  • Energy Drinks* / adverse effects
  • Humans
  • Prognosis
  • Protective Factors
  • Recommended Dietary Allowances
  • Risk Assessment
  • Risk Factors


  • Central Nervous System Stimulants
  • Coffee
  • Caffeine