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Review
, 14, 10-16
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The Non-Reconstructive Treatment of Complete ACL Tear With Biological Enhancement in Clinical and Preclinical Studies: A Systematic Review

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Review

The Non-Reconstructive Treatment of Complete ACL Tear With Biological Enhancement in Clinical and Preclinical Studies: A Systematic Review

Yue Li et al. Asia Pac J Sports Med Arthrosc Rehabil Technol.

Abstract

Introduction: There is still controversy regarding the bio-enhanced non-reconstructive ACL treatment.

Materials and methods: A search for articles in databases was performed in February 2017. The objective and subjective evaluations of clinical studies and biomechanical and histological data of preclinical studies were extracted.

Results: Eighteen articles were included for analysis. In clinical studies, although subjective scores were significantly improved, the rate of re-operation rate was high. In preclinical studies, bio-enhancing techniques demonstrated promotion of the healing of ACL.

Conclusions: The efficacy of biological enhancement cannot be validated in clinical studies. Preclinical studies showed improved biomechanical and healing potential.

Figures

Fig. 1
Fig. 1
PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart.

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