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The Application of Supercritical Fluid Extraction in Phenolic Compounds Isolation From Natural Plant Materials

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Review

The Application of Supercritical Fluid Extraction in Phenolic Compounds Isolation From Natural Plant Materials

Katarzyna Tyśkiewicz et al. Molecules.

Abstract

The separation of phenolic compounds by supercritical fluid extraction has been widely studied throughout the last two decades. This is evidenced by a number of publications and articles. Supercritical fluid extraction (SFE) has become thus the effective method of separating the mentioned group of compounds. On the other hand, SFE is a beneficial approach in plant waste materials utilization and reduction of environmental burdens caused by the wastes. The aim of the study is to gather and systematize available information on the phenolic compounds separation that have been reported so far as well as to evaluate whether there is one optimal supercritical fluid extraction method for the phenolic compounds.

Keywords: anthocyanins; carbon dioxide; extraction techniques; flavonoids; phenolic compounds.

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Evolution in the number of papers with the keyword “phenolic compounds” (Science direct, June 2018).
Figure 2
Figure 2
The structure of phenolic acids (R1=R2=H—cinnamic acid; R1=OH, R2=H—p-coumaric acid; R1=R2=OH—caffeic acid; R1=OH, R2=OCH3—ferulic acid).
Figure 3
Figure 3
The structure of benzoic acid derivatives (R1=R2=H—hydroxybenzoic acid; R1=OH, R2=H—protocatechuic acid; R1=OCH3, R2=H—vanillic acid; R1=R2=OH—gallic acid; R1=R2=OCH3—syringic acid).
Figure 4
Figure 4
The structure of isoflavones (R1=R3=OH, R2=H—daidzein; R1=O-Glc, R2=H, R3=OH—daidzin; R1=R2=R3=OH—genistein; R1=O-Glc, R2=R3=OH—genistin).
Figure 5
Figure 5
Application of SFE in phenolic compounds extraction from plant materials.

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References

    1. De Melo M.M.R., Silvestre A.J.D., Silva C.M. Supercritical fluids extraction of vegetable matrices; applications, trends and future perspectives of a convincing green technology. J. Supercrit. Fluids. 2017;92:115–176. doi: 10.1016/j.supflu.2014.04.007. - DOI
    1. Manna L., Bugnone C., Banchero M. Valorization of hazelnut, coffee and grape wastes through supercritical fluid extraction of triglycerides and polyphenols. J. Supercrit. Fluids. 2015;104:204–211. doi: 10.1016/j.supflu.2015.06.012. - DOI
    1. Soobrattee M.A., Neergheen V.S., Luximan-Ramma A., Aruoma O.J., Bahorun T. Phenolics as potential antioxidant therapeutic agents: Mechanism and actions. Mutat. Res. Fund. Mol. 2005;579:200–213. doi: 10.1016/j.mrfmmm.2005.03.023. - DOI - PubMed
    1. Adil I.H., Cetin H.I., Yener M.E., Bayindirli A. Subcritical (carbon dioxide + ethanol) extraction of polyphenols from apple and peach pomaces, and determination of the antioxidant activities of the extracts. J. Supercrit. Fluids. 2007;43:55–63. doi: 10.1016/j.supflu.2007.04.012. - DOI
    1. Liu J., Lin S., Wang Z., Wang C., Wang E., Zhang Y., Liu J. Supercritical fluid extraction of flavonoids from Maydis stigma and its nitrite-scavenging ability. Food Bioprod. Process. 2011;89:333–339. doi: 10.1016/j.fbp.2010.08.004. - DOI

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