Neuromuscular blockers and reversal agents and their impact on anesthesia practice

Best Pract Res Clin Anaesthesiol. 2018 Jun;32(2):203-211. doi: 10.1016/j.bpa.2018.06.004. Epub 2018 Jul 2.

Abstract

Neuromuscular blockers have long been an intricate part of the anesthesia regimen. The scientific progress in pharmacology and physiology has strengthened their clinical relevance, has helped to delineate with precision their medical role, and has enhanced the safety and effectiveness of their use. New frontiers in research will define further the role of these agents in modern anesthesia practice and guide their expanding and discrete clinical applications.

Keywords: neuromuscular blockade reversal; neuromuscular blockers; rapid sequence induction; sugammadex; supraglottic airway device.

Publication types

  • Review

MeSH terms

  • Anesthesia, General / adverse effects
  • Anesthesia, General / methods*
  • Anesthesia, General / trends
  • Humans
  • Narcotic Antagonists / administration & dosage
  • Neuromuscular Blocking Agents / administration & dosage*
  • Neuromuscular Blocking Agents / adverse effects
  • Sugammadex / administration & dosage*

Substances

  • Narcotic Antagonists
  • Neuromuscular Blocking Agents
  • Sugammadex