Physical Activity in Liver Transplantation: A Patient's and Physicians' Experience

Adv Ther. 2018 Nov;35(11):1729-1734. doi: 10.1007/s12325-018-0797-7. Epub 2018 Oct 16.


Liver transplantation has become a highly standardized, acceptable option for selected patients with end-stage liver disease and/or hepatocellular carcinoma in the setting of cirrhosis. Both conditions are associated with loss of skeletal muscle mass (sarcopenia) and physical deconditioning. Both conditions result in a dramatic decrease in the patients' quality of life, negatively impacting on the pre- and post-transplant prognosis. In this context, awareness of the advantages of physical activity in both the pre- and post-transplant setting is key. However, the importance of regular, individualized and patient-adapted physical activity is still understudied and underestimated. This article describes a three-sided perspective on the importance of physical activity in the setting of liver transplantation, including a patient's, transplant surgeon's and hepatologist's point of view.

Keywords: Exercise; Liver cirrhosis; Liver transplantation; Malnutrition; Physical activity; Reconditioning; Sarcopenia.

MeSH terms

  • Adult
  • Aged
  • Exercise / physiology*
  • Exercise / psychology
  • Female
  • Humans
  • Liver Diseases / surgery*
  • Liver Transplantation / psychology*
  • Liver Transplantation / rehabilitation*
  • Male
  • Middle Aged
  • Physical Therapy Modalities*
  • Physicians / psychology*
  • Quality of Life / psychology*

Associated data

  • figshare/10.6084/m9.figshare.7093529