The Exacerbation of Hemicrania Continua Mimics Trigeminal Neuralgia

Intern Med. 2019 Mar 1;58(5):723-725. doi: 10.2169/internalmedicine.1561-18. Epub 2018 Oct 17.


We report the case of a 46-year-old man with hemicrania continua presenting as exacerbations mimicking trigeminal neuralgia. The patient was tentatively diagnosed with trigeminal neuralgia, and treatment with various combinations of drugs was performed after the onset of pain. However, when the condition of the patient did not improve, we suspected hemicrania continua, and treatment with indomethacin was initiated. There was a marked alleviation of his pain within 24 hours. Thus, clinicians should be aware that the duration and frequency of exacerbations of hemicrania continua are variable.

Keywords: indomethacin; tooth extraction; trigeminal autonomic cephalalgias.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Diagnosis, Differential
  • Humans
  • Indomethacin / therapeutic use
  • Male
  • Middle Aged
  • Trigeminal Autonomic Cephalalgias / diagnosis*
  • Trigeminal Autonomic Cephalalgias / drug therapy
  • Trigeminal Neuralgia / diagnosis*


  • Anti-Inflammatory Agents, Non-Steroidal
  • Indomethacin