Leishmaniasis in Northern Syria during Civil War

Emerg Infect Dis. 2018 Nov;24(11):1973-1981. doi: 10.3201/eid2411.172146.


Since the onset of the ongoing civil war in Syria, the governmental surveillance system for leishmaniasis has lost access to provinces of northern Syria. The MENTOR Initiative, an international not-for-profit organization, was commissioned to implement an integrated leishmaniasis control program, providing an opportunity to reassess the epidemiology of leishmaniasis in northern Syria. Epidemiologic data and biologic samples for molecular species diagnostics were collected from collaborating local health centers. Incidence peaked in March 2015 at 7,743 estimated monthly cases. High levels of transmission were observed in traditional endemic regions but extended to previously hypoendemic regions, such as Al-Raqqa and Al-Hasakah. Incidence decreased to 3,209 in July 2015. Data indicate that the prewar trend of increasing incidence of cutaneous leishmaniasis accelerated during the beginning of armed conflict but declined after implementation of the comprehensive control program by the MENTOR Initiative. Molecular analysis revealed a spectrum of Leishmania species and sporadic cases of visceral leishmaniasis.

Keywords: Aleppo boil; Leishmania; Syria; civil war; conflict; epidemiology; leishmaniasis; parasites.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Female
  • Geography
  • Humans
  • Incidence
  • Leishmania / genetics
  • Leishmania / isolation & purification*
  • Leishmaniasis / epidemiology*
  • Leishmaniasis / parasitology
  • Leishmaniasis, Cutaneous / epidemiology*
  • Leishmaniasis, Cutaneous / parasitology
  • Leishmaniasis, Visceral / epidemiology*
  • Leishmaniasis, Visceral / parasitology
  • Male
  • Middle Aged
  • Syria / epidemiology
  • Warfare
  • Young Adult