Noonan Syndrome

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.


Noonan syndrome is a genetically inherited disease with heterogeneous, phenotypic manifestations. Gene mutations involve the RAAS/MAPK (mitogen-activated protein kinase) signaling pathway. The patient presentation can range from mild to severe. Thus, Noonan syndrome is typically a clinical diagnosis.

Publication types

  • Study Guide