Pediatric Quality of Life Inventory (PedsQL) 3.2 Diabetes Module for youth with Type 2 diabetes: reliability and validity

J W Varni; A M Delamater; K K Hood; J K Raymond; N T Chang; K A Driscoll; J C Wong; J P Yi-Frazier; E K Grishman; M A Faith; S D Corathers; J C Kichler; J L Miller; E M Doskey; V P Aguirre; R W Heffer; D P Wilson; Pediatric Quality of Life Inventory 3.2 Diabetes Module Testing Study Consortium

doi:10.1111/dme.13841

Pediatric Quality of Life Inventory (PedsQL) 3.2 Diabetes Module for youth with Type 2 diabetes: reliability and validity

Diabet Med. 2019 Apr;36(4):465-472. doi: 10.1111/dme.13841. Epub 2018 Nov 20.

Authors

J W Varni¹, A M Delamater², K K Hood³, J K Raymond⁴, N T Chang⁴, K A Driscoll⁵, J C Wong⁶, J P Yi-Frazier⁷, E K Grishman⁸, M A Faith⁸, S D Corathers⁹, J C Kichler¹⁰, J L Miller¹¹, E M Doskey¹², V P Aguirre¹³, R W Heffer¹³, D P Wilson¹⁴; Pediatric Quality of Life Inventory 3.2 Diabetes Module Testing Study Consortium

Affiliations

¹ Department of Pediatrics, College of Medicine and Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, College Station, TX.
² Department of Pediatrics, Mailman Center for Child Development, University of Miami Miller School of Medicine, Miami, FL.
³ Division of Pediatric Endocrinology and Diabetes, Stanford University School of Medicine, Stanford, CA.
⁴ Center for Endocrinology, Diabetes, & Metabolism, Children's Hospital Los Angeles, Los Angeles, CA.
⁵ Department of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Denver, Denver, CO.
⁶ The Madison Clinic for Pediatric Diabetes and Department of Pediatrics, Division of Endocrinology, University of California San Francisco, San Francisco, CA.
⁷ Seattle Children's Research Institute, Seattle, WA.
⁸ Department of Pediatrics, Division of Pediatric Endocrinology, University of Texas Southwestern Medical Center, Dallas, TX.
⁹ Department of Pediatrics, Division of Endocrinology, Cincinnati, OH.
¹⁰ Department of Pediatrics, Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH.
¹¹ Division of Pediatric Endocrinology, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL.
¹² Department of Educational Psychology, Texas A&M University, College Station, College Station, TX.
¹³ Department of Psychological and Brain Sciences, Texas A&M University, College Station, College Station, TX.
¹⁴ Cook Children's Medical Center, Fort Worth, TX, USA.

PMID: 30343524
DOI: 10.1111/dme.13841

Abstract

Aim: To test the measurement properties of the revised and updated Pediatric Quality of Life Inventory (PedsQL) 3.2 Diabetes Module originally developed in Type 1 diabetes in youth with Type 2 diabetes.

Methods: The PedsQL 3.2 Diabetes Module and PedsQL Generic Core Scales were administered in a field test study to 100 young people aged 9-25 years with Type 2 diabetes. Factor analysis was conducted to determine the factor structure of the items.

Results: The 15-item Diabetes Symptoms Summary Score and 12-item Type 2-specific Diabetes Management Summary Score were empirically derived through factor analysis. The Diabetes Symptoms and Type 2-specific Diabetes Management Summary Scores showed acceptable to excellent reliability across the age groups tested (α = 0.85-0.94). The Diabetes Symptoms and Type 2-specific Diabetes Management Summary Scores evidenced construct validity through large effect size correlations with the Generic Core Scales Total Scale Score (r = 0.67 and 0.57, respectively). HbA_1c was correlated with the Diabetes Symptoms and Type 2-specific Diabetes Management Summary Scores (r = -0.13 and -0.22). Minimal clinically important difference (MCID) scores were 5.91 and 7.39 for the Diabetes Symptoms and Type 2-specific Diabetes Management Summary Scores.

Conclusions: The PedsQL 3.2 Diabetes Module Diabetes Symptoms Summary Score and Type 2-specific Diabetes Management Summary Score exhibited satisfactory measurement properties for use as youth self-reported diabetes symptoms and diabetes management outcomes for clinical research and clinical practice for young people with Type 2 diabetes.

Publication types

Evaluation Study

MeSH terms

Adolescent
Adult
Age Factors
Age of Onset
Child
Diabetes Mellitus, Type 1 / diagnosis
Diabetes Mellitus, Type 1 / psychology
Diabetes Mellitus, Type 2 / diagnosis
Diabetes Mellitus, Type 2 / epidemiology*
Diabetes Mellitus, Type 2 / psychology
Feasibility Studies
Female
Health Status*
Humans
Male
Patient Reported Outcome Measures
Psychometrics / methods*
Quality of Life*
Reproducibility of Results
Surveys and Questionnaires* / standards
Young Adult