Topical use of tranexamic acid for the management of post-procedural rectal bleeding

Am J Emerg Med. 2019 Jan;37(1):173.e3-173.e4. doi: 10.1016/j.ajem.2018.09.037. Epub 2018 Sep 25.


Tranexamic acid (TXA) is increasingly used in the Emergency Department (ED). While the intravenous form has been extensively studied and used, it's utility in a topical formulation is not as widespread. Its reported use in the ED is mostly for control of epistaxis. We present a case of a 61 year old male with post-procedural rectal bleeding, responsive to topical application of tranexamic acid. This case report demonstrates another novel application of TXA in emergency care.

Keywords: Rectal bleeding; Topical; Tranexamic acid.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Antifibrinolytic Agents / administration & dosage*
  • Biopsy, Needle / adverse effects*
  • Emergency Service, Hospital
  • Gastrointestinal Hemorrhage / drug therapy*
  • Gastrointestinal Hemorrhage / etiology
  • Hemostatic Techniques*
  • Humans
  • Male
  • Middle Aged
  • Rectum*
  • Tranexamic Acid / administration & dosage*


  • Antifibrinolytic Agents
  • Tranexamic Acid