Transient natural killer cell dysfunction associated with interleukin-18 overproduction in systemic juvenile idiopathic arthritis

Pediatr Int. 2018 Oct;60(10):984-985. doi: 10.1111/ped.13679.

Authors

Maiko Takakura¹, Masaki Shimizu¹, Tadafumi Yakoyama¹, Mao Mizuta¹, Akihiro Yachie¹

Affiliation

¹ Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

PMID: 30345698
DOI: 10.1111/ped.13679

No abstract available

Keywords: interleukin-18; macrophage activation syndrome; systemic juvenile idiopathic arthritis.

MeSH terms

Arthritis, Juvenile / blood
Arthritis, Juvenile / complications*
Cell Culture Techniques
Child
Child, Preschool
Female
Humans
Interleukin-18 / blood*
Killer Cells, Natural / pathology*
Macrophage Activation Syndrome / etiology*
Male
Young Adult

Substances

IL18 protein, human
Interleukin-18