Motion-robust reconstruction of multishot diffusion-weighted images without phase estimation through locally low-rank regularization

Magn Reson Med. 2019 Feb;81(2):1181-1190. doi: 10.1002/mrm.27488. Epub 2018 Oct 22.


Purpose: The goal of this work is to propose a motion robust reconstruction method for diffusion-weighted MRI that resolves shot-to-shot phase mismatches without using phase estimation.

Methods: Assuming that shot-to-shot phase variations are slowly varying, spatial-shot matrices can be formed using a local group of pixels to form columns, in which each column is from a different shot (excitation). A convex model with a locally low-rank constraint on the spatial-shot matrices is proposed. In vivo brain and breast experiments were performed to evaluate the performance of the proposed method.

Results: The proposed method shows significant benefits when the motion is severe, such as for breast imaging. Furthermore, the resulting images can be used for reliable phase estimation in the context of phase-estimation-based methods to achieve even higher image quality.

Conclusion: We introduced the shot-locally low-rank method, a reconstruction technique for multishot diffusion-weighted MRI without explicit phase estimation. In addition, its motion robustness can be beneficial to neuroimaging and body imaging.

Keywords: locally low-rank; motion-induced phase; multishot diffusion-weighted imaging; virtual conjugate shot.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Artifacts
  • Brain / diagnostic imaging*
  • Breast / diagnostic imaging*
  • Diffusion Magnetic Resonance Imaging
  • Diffusion Tensor Imaging
  • Fourier Analysis
  • Healthy Volunteers
  • Humans
  • Image Interpretation, Computer-Assisted / methods
  • Image Processing, Computer-Assisted / methods*
  • Motion
  • Reproducibility of Results