False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma-A Caution for Reporting Physicians

Paul Boré; Renaud Descourt; Luc Ollivier; Pierre-Yves Le Roux; Ronan Abgral

doi:10.3389/fmed.2018.00275

False Positive 18F-FDG Positron Emission Tomography Findings in Schwannoma-A Caution for Reporting Physicians

Front Med (Lausanne). 2018 Oct 8:5:275. doi: 10.3389/fmed.2018.00275. eCollection 2018.

Authors

Paul Boré¹, Renaud Descourt¹, Luc Ollivier², Pierre-Yves Le Roux³, Ronan Abgral³

Affiliations

¹ Service d'Oncologie Médicale, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, France.
² Service de Radiothérapie, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, France.
³ Service de Médecine Nucléaire, EA 3878 (GETBO) IF 148, Centre Hospitalier Régional et Universitaire de Brest, Université de Bretagne Occidentale, Brest, France.

Abstract

Schwannoma is a rare source of false-positive 18F-fluorodeoxyglucose (18F-FDG) uptake in Positron-emission tomography (PET/CT), inducing potential errors in staging of several solid cancer, with implications for patient management. This clinical case reports the situation of a patient undergoing an 18F-FDG-PET/CT for initial staging of an ovarian adenocarcinoma. We found a high paramediastinal hypermetabolic mass suspicious of remote extension or secondary synchronous primitive tumor. The biopsy finally reveals a histopathology of Schwannoma, allowing the patient to be eligible for a surgical procedure of her ovarian adenocarcinoma by rejecting the hypothesis of malignancy.

Keywords: mediastinal neoplasms; neoplasm staging; ovarian neoplasms; positron-emission tomography; schwannoma.

Publication types

Case Reports